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Attenuation of VEGFR-2 Expression by sFlt-1 and Low Oxygen in Human Placenta

Vascular endothelial growth factor receptor 2 (VEGFR-2), the primary receptor for VEGF, is crucial for normal endothelial function. sFlt-1, a truncated and soluble form of VEGFR-1 which binds and inhibits VEGF, is increased in preeclampsia and is positively regulated by low oxygen. Here, we investig...

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Библиографические подробности
Главные авторы: Nevo, Ori, Lee, Dennis K., Caniggia, Isabella
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2013
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3834253/
https://ncbi.nlm.nih.gov/pubmed/24260556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0081176
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