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Nanobody-based binding assay for the discovery of potent inhibitors of CFTR inhibitory factor (Cif)
Lead identification and optimization are essential steps in the development of a new drug. It requires cost-effective, selective and sensitive chemical tools. Here, we report a novel method using nanobodies that allows the efficient screening for potent ligands. The method is illustrated with the cy...
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| Publié dans: | Anal Chim Acta |
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| Auteurs principaux: | , , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2019
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6426448/ https://ncbi.nlm.nih.gov/pubmed/30832908 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.aca.2018.12.060 |
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