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Enhancing Protein Stability with Genetically Encoded Noncanonical Amino Acids

The ability to add noncanonical amino acids to the genetic code may allow one to evolve proteins with new or enhanced properties using a larger set of building blocks. To this end, we have been able to select mutant proteins with enhanced thermal properties from a library of E. coli homoserine o-suc...

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Bibliografiske detaljer
Udgivet i:J Am Chem Soc
Main Authors: Li, Jack C., Liu, Tao, Wang, Yan, Mehta, Angad P., Schultz, Peter G.
Format: Artigo
Sprog:Inglês
Udgivet: 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6426444/
https://ncbi.nlm.nih.gov/pubmed/30433771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.8b07157
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