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Protein Crosslinking by Genetically Encoded Noncanonical Amino Acids with Reactive Aryl Carbamate Side Chains

The use of genetically encoded noncanonical amino acids (ncAAs) to construct crosslinks within or between proteins has emerged as a useful method to enhance protein stability, investigate protein-protein interactions and improve the pharmacological properties of proteins. Here we report ncAAs with a...

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Bibliografiske detaljer
Udgivet i:Angew Chem Int Ed Engl
Main Authors: Xuan, Weimin, Shao, Sida, Schultz, Peter G.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5543777/
https://ncbi.nlm.nih.gov/pubmed/28371162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201611841
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