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A New Strategy for Creating Noncanonical Amino Acid Dependent Organisms

The use of noncanonical amino acids (ncAAs) to control an organism's viability provides a strategy for the development of conditional ‘kill switches’ for live vaccines or engineered human cells. Here we report an approach inspired by the posttranslational acetylation/deacetylation of lysine res...

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Bibliografiske detaljer
Udgivet i:Angew Chem Int Ed Engl
Main Authors: Xuan, Weimin, Schultz, Peter G.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5580492/
https://ncbi.nlm.nih.gov/pubmed/28593724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201703553
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