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Enhancing Protein Stability with Genetically Encoded Noncanonical Amino Acids

The ability to add noncanonical amino acids to the genetic code may allow one to evolve proteins with new or enhanced properties using a larger set of building blocks. To this end, we have been able to select mutant proteins with enhanced thermal properties from a library of E. coli homoserine o-suc...

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Foilsithe in:J Am Chem Soc
Main Authors: Li, Jack C., Liu, Tao, Wang, Yan, Mehta, Angad P., Schultz, Peter G.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2018
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6426444/
https://ncbi.nlm.nih.gov/pubmed/30433771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.8b07157
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