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Interplay between innate immunity and Alzheimer’s disease: APOE and TREM2 in the spotlight
Alzheimer’s disease is more than a pure proteopathy. Chronic neuroinflammation stands out during the pathogenesis of the disease and in turn modulates disease progression. The central nervous system (CNS) is separated from the blood circulation by the blood-brain barrier. In Alzheimer’s disease, neu...
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| Опубликовано в: : | Nat Rev Immunol |
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| Главные авторы: | , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2018
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6425488/ https://ncbi.nlm.nih.gov/pubmed/30140051 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41577-018-0051-1 |
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