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Interplay between innate immunity and Alzheimer’s disease: APOE and TREM2 in the spotlight

Alzheimer’s disease is more than a pure proteopathy. Chronic neuroinflammation stands out during the pathogenesis of the disease and in turn modulates disease progression. The central nervous system (CNS) is separated from the blood circulation by the blood-brain barrier. In Alzheimer’s disease, neu...

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Detaylı Bibliyografya
Yayımlandı:Nat Rev Immunol
Asıl Yazarlar: Shi, Yang, Holtzman, David M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2018
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6425488/
https://ncbi.nlm.nih.gov/pubmed/30140051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41577-018-0051-1
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