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New insights into the role of TREM2 in Alzheimer’s disease

Alzheimer’s disease (AD) is the leading cause of dementia. The two histopathological markers of AD are amyloid plaques composed of the amyloid-β (Aβ) peptide, and neurofibrillary tangles of aggregated, abnormally hyperphosphorylated tau protein. The majority of AD cases are late-onset, after the age...

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Detalhes bibliográficos
Publicado no:Mol Neurodegener
Main Authors: Gratuze, Maud, Leyns, Cheryl E. G., Holtzman, David M.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6302500/
https://ncbi.nlm.nih.gov/pubmed/30572908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13024-018-0298-9
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