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New insights into the role of TREM2 in Alzheimer’s disease

Alzheimer’s disease (AD) is the leading cause of dementia. The two histopathological markers of AD are amyloid plaques composed of the amyloid-β (Aβ) peptide, and neurofibrillary tangles of aggregated, abnormally hyperphosphorylated tau protein. The majority of AD cases are late-onset, after the age...

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Dettagli Bibliografici
Pubblicato in:Mol Neurodegener
Autori principali: Gratuze, Maud, Leyns, Cheryl E. G., Holtzman, David M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6302500/
https://ncbi.nlm.nih.gov/pubmed/30572908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13024-018-0298-9
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