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Alzheimer's disease risk alleles in TREM2 illuminate innate immunity in Alzheimer's disease
Genetic studies have provided the best evidence for cause and effect relationships in Alzheimer's disease (AD). Indeed, the identification of deterministic mutations in the APP, PSEN1 and PSEN2 genes and subsequent preclinical studies linking these mutations to alterations in Aβ production and...
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| Main Authors: | , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
BioMed Central
2013
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3706774/ https://ncbi.nlm.nih.gov/pubmed/23692967 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/alzrt178 |
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