Nucleic Acids as a Nature‐Inspired Scaffold for Macromolecular Prodrugs of Nucleoside Analogues

Macromolecular prodrugs (MP) built on the natural phosphodiester and deoxyribose backbone are developed using marketed antiviral nucleoside analogues. These MP are synthesized using automated synthesis, have defined molecular composition, and have a natural mechanism for drug release. These unique a...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Adv Sci (Weinh)
Egile Nagusiak: Krüger, Franziska, Kumar, Vipin, Monge, Pere, Conzelmann, Carina, Smith, Nikaïa, Gothelf, Kurt V., Tolstrup, Martin, Münch, Jan, Zelikin, Alexander N.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: John Wiley and Sons Inc. 2019
Gaiak:
Communications
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6425433/
https://ncbi.nlm.nih.gov/pubmed/30937274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/advs.201802095
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