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The Interactome of Palmitoyl-Protein Thioesterase 1 (PPT1) Affects Neuronal Morphology and Function

Palmitoyl-protein thioesterase 1 (PPT1) is a depalmitoylation enzyme that is mutated in cases of neuronal ceroid lipofuscinosis (NCL). The hallmarks of the disease include progressive neurodegeneration and blindness, as well as seizures. In the current study, we identified 62 high-confident PPT1-bin...

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Detalles Bibliográficos
Publicado en:Front Cell Neurosci
Main Authors: Sapir, Tamar, Segal, Michal, Grigoryan, Gayane, Hansson, Karin M., James, Peter, Segal, Menahem, Reiner, Orly
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6424868/
https://ncbi.nlm.nih.gov/pubmed/30918483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2019.00092
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