The Interactome of Palmitoyl-Protein Thioesterase 1 (PPT1) Affects Neuronal Morphology and Function

Palmitoyl-protein thioesterase 1 (PPT1) is a depalmitoylation enzyme that is mutated in cases of neuronal ceroid lipofuscinosis (NCL). The hallmarks of the disease include progressive neurodegeneration and blindness, as well as seizures. In the current study, we identified 62 high-confident PPT1-bin...

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Vydáno v:Front Cell Neurosci
Hlavní autoři: Sapir, Tamar, Segal, Michal, Grigoryan, Gayane, Hansson, Karin M., James, Peter, Segal, Menahem, Reiner, Orly
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2019
Témata:
Neuroscience
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6424868/
https://ncbi.nlm.nih.gov/pubmed/30918483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2019.00092
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