The Interactome of Palmitoyl-Protein Thioesterase 1 (PPT1) Affects Neuronal Morphology and Function

Palmitoyl-protein thioesterase 1 (PPT1) is a depalmitoylation enzyme that is mutated in cases of neuronal ceroid lipofuscinosis (NCL). The hallmarks of the disease include progressive neurodegeneration and blindness, as well as seizures. In the current study, we identified 62 high-confident PPT1-bin...

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發表在:Front Cell Neurosci
Main Authors: Sapir, Tamar, Segal, Michal, Grigoryan, Gayane, Hansson, Karin M., James, Peter, Segal, Menahem, Reiner, Orly
格式: Artigo
語言:Inglês
出版: Frontiers Media S.A. 2019
主題:
Neuroscience
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6424868/
https://ncbi.nlm.nih.gov/pubmed/30918483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2019.00092
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