Activity and structural analysis of GRL-117C: a novel small molecule CCR5 inhibitor active against R5-tropic HIV-1s

CCR5 is a member of the G-protein coupled receptor family that serves as an essential co-receptor for cellular entry of R5-tropic HIV-1, and is a validated target for therapeutics against HIV-1 infections. In the present study, we designed and synthesized a series of novel small CCR5 inhibitors and...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Nakata, Hirotomo, Maeda, Kenji, Das, Debananda, Chang, Simon B., Matsuda, Kouki, Rao, Kalapala Venkateswara, Harada, Shigeyoshi, Yoshimura, Kazuhisa, Ghosh, Arun K., Mitsuya, Hiroaki
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6423129/
https://ncbi.nlm.nih.gov/pubmed/30886166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-41080-w
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados