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Establishment of a multi-component dietary bioactive human equivalent dose to delete damaged Lgr5(+) stem cells using a mouse colon tumor initiation model

Multi-component therapy has gained interest for its potential to synergize and subsequently lower the effective dose of each constituent required to reduce colon cancer risk. We have previously demonstrated that rapidly cycling Lgr5(+) stem cells are exquisitely sensitive to extrinsic dietary factor...

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Bibliografske podrobnosti
izdano v:Eur J Cancer Prev
Main Authors: Kim, Eunjoo, Wright, Gus A., Zoh, Roger S., Patil, Bhimanagouda S., Jayaprakasha, Guddadarangavvanahally K., Callaway, Evelyn S., Ivanov, Ivan, Turner, Nancy D., Chapkin, Robert S.
Format: Artigo
Jezik:Inglês
Izdano: 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6422758/
https://ncbi.nlm.nih.gov/pubmed/30234553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CEJ.0000000000000465
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