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Establishment of a multi-component dietary bioactive human equivalent dose to delete damaged Lgr5(+) stem cells using a mouse colon tumor initiation model

Multi-component therapy has gained interest for its potential to synergize and subsequently lower the effective dose of each constituent required to reduce colon cancer risk. We have previously demonstrated that rapidly cycling Lgr5(+) stem cells are exquisitely sensitive to extrinsic dietary factor...

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Podrobná bibliografie
Vydáno v:Eur J Cancer Prev
Hlavní autoři: Kim, Eunjoo, Wright, Gus A., Zoh, Roger S., Patil, Bhimanagouda S., Jayaprakasha, Guddadarangavvanahally K., Callaway, Evelyn S., Ivanov, Ivan, Turner, Nancy D., Chapkin, Robert S.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6422758/
https://ncbi.nlm.nih.gov/pubmed/30234553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CEJ.0000000000000465
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