Repurposing of the antihistamine chlorcyclizine and related compounds for treatment of hepatitis C virus infection

Hepatitis C virus (HCV) infection affects an estimated 185 million people worldwide, with chronic infection often leading to liver cirrhosis and hepatocellular carcinoma. Although HCV is curable, there is an unmet need for the development of effective and affordable treatment options. Through a cell...

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Detalhes bibliográficos
Publicado no:Sci Transl Med
Main Authors: He, Shanshan, Lin, Billy, Chu, Virginia, Hu, Zongyi, Hu, Xin, Xiao, Jingbo, Wang, Amy Q., Schweitzer, Cameron J., Li, Qisheng, Imamura, Michio, Hiraga, Nobuhiko, Southall, Noel, Ferrer, Marc, Zheng, Wei, Chayama, Kazuaki, Marugan, Juan J., Liang, T. Jake
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6420960/
https://ncbi.nlm.nih.gov/pubmed/25855495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3010286
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