Metabolic heterogeneity underlies reciprocal fates of T(H)17 cell stemness and plasticity

A defining feature of adaptive immunity is the development of long-lived memory T cells to curtail infection. Recent studies have identified a unique stem-like T cell subset in exhausted CD8(+) T cells in chronic infection(1–3), but it remains unclear whether CD4(+) T cell subsets with similar featu...

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Detalhes bibliográficos
Publicado no:Nature
Main Authors: Karmaus, Peer W F, Chen, Xiang, Lim, Seon Ah, Herrada, Andrés A, Nguyen, Thanh-Long M, Xu, Beisi, Dhungana, Yogesh, Rankin, Sherri, Chen, Wenan, Rosencrance, Celeste, Yang, Kai, Fan, Yiping, Cheng, Yong, Easton, John, Neale, Geoffrey, Vogel, Peter, Chi, Hongbo
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6420879/
https://ncbi.nlm.nih.gov/pubmed/30568299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-018-0806-7
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