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Critical role of the finger loop in arrestin binding to the receptors

We tested the interactions with four different G protein-coupled receptors (GPCRs) of arrestin-3 mutants with substitutions in the four loops, three of which contact the receptor in the structure of the arrestin-1-rhodopsin complex. Point mutations in the loop at the distal tip of the N-domain (Glu1...

詳細記述

保存先:
書誌詳細
出版年:PLoS One
主要な著者: Zheng, Chen, Tholen, Jonas, Gurevich, Vsevolod V.
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6420155/
https://ncbi.nlm.nih.gov/pubmed/30875392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0213792
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