HSF1: Essential for Myeloma Cell Survival and A Promising Therapeutic Target

PURPOSE: Myeloma is a plasma cell malignancy characterized by the overproduction of immunoglobulin and is therefore susceptible to therapies targeting protein homeostasis. We hypothesized that heat shock factor 1 (HSF1) was an attractive therapeutic target for myeloma due to its direct regulation of...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: Fok, Jacqueline H L, Hedayat, Somaieh, Zhang, Lei, Aronson, Lauren I., Mirabella, Fabio, Pawlyn, Charlotte, Bright, Michael D., Wardell, Christopher P., Keats, Jonathan J, De Billy, Emmanuel, Rye, Carl S., Chessum, Nicola E. A., Jones, Keith, Morgan, Gareth J., Eccles, Suzanne A., Workman, Paul, Davies, Faith E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6420136/
https://ncbi.nlm.nih.gov/pubmed/29391353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-17-1594
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados