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Memory CD4(+) T cells are generated in the human fetal intestine

The fetus is thought to be protected from exposure to foreign antigens, yet CD45RO(+) T cells reside in the fetal intestine. Here we combined functional assays with mass cytometry, single-cell RNA-sequencing and high-throughput T cell antigen receptor (TCR) sequencing to characterize the CD4(+) T ce...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Nat Immunol
Egile Nagusiak: Li, Na, van Unen, Vincent, Abdelaal, Tamim, Guo, Nannan, Kasatskaya, Sofya A., Ladell, Kristin, McLaren, James E., Egorov, Evgeny S., Izraelson, Mark, Chuva de Sousa Lopes, Susana M., Höllt, Thomas, Britanova, Olga V, Eggermont, Jeroen, de Miranda, Noel F.C.C., Chudakov, Dmitriy M., Price, David A., Lelieveldt, Boudewijn P.F., Koning, Frits
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2019
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6420108/
https://ncbi.nlm.nih.gov/pubmed/30664737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41590-018-0294-9
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