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Physicochemical characterization and phase I study of CMAB008, an infliximab biosimilar produced by a different expression system
BACKGROUND: Infliximab (Remicade), a chimeric monoclonal antibody against human TNFα, will inevitably face competition from biosimilar products, because of its effectiveness in autoimmune diseases and rapidly increasing market demand. According to guidelines for biosimilar development, the “biosimil...
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| Gepubliceerd in: | Drug Des Devel Ther |
|---|---|
| Hoofdauteurs: | , , , , , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Dove Medical Press
2019
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6420106/ https://ncbi.nlm.nih.gov/pubmed/30880912 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S170913 |
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