Characterization of alanine to valine sequence variants in the Fc region of nivolumab biosimilar produced in Chinese hamster ovary cells

Nivolumab is a therapeutic fully human IgG4 antibody to programmed death 1 (PD-1). In this study, a nivolumab biosimilar, which was produced in our laboratory, was analyzed and characterized. Sequence variants that contain undesired amino acid sequences may cause concern during biosimilar bioprocess...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:MAbs
Main Authors: Li, Yantao, Fu, Tuo, Liu, Tao, Guo, Huaizu, Guo, Qingcheng, Xu, Jin, Zhang, Dapeng, Qian, Weizhu, Dai, Jianxin, Li, Bohua, Guo, Yajun, Hou, Sheng, Wang, Hao
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2016
Assuntos:
Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4968099/
https://ncbi.nlm.nih.gov/pubmed/27050807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2016.1172150
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados