Comparison of the Inhibition Mechanisms of Adalimumab and Infliximab in Treating Tumor Necrosis Factor α-Associated Diseases from a Molecular View

TNFα-targeting therapy with the use of the drugs Etanercept, Infliximab, and Adalimumab is used in the clinical treatment of various inflammatory and immune diseases. Although all of these reagents function to disrupt the interaction between TNFα and its receptors, clinical investigations showed the...

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Detalhes bibliográficos
Main Authors: Hu, Shi, Liang, Shuaiyi, Guo, Huaizu, Zhang, Dapeng, Li, Hui, Wang, Xiaoze, Yang, Weili, Qian, Weizhu, Hou, Sheng, Wang, Hao, Guo, Yajun, Lou, Zhiyong
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3779706/
https://ncbi.nlm.nih.gov/pubmed/23943614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.491530
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