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Bradykinin receptor deficiency or antagonism do not impact the host response during gram-negative pneumonia-derived sepsis

BACKGROUND: Kinins are short peptides with a wide range of proinflammatory properties that are generated from kininogens in the so-called kallikrein-kinin system. Kinins exert their biological activities through stimulation of two distinct receptor subtypes, the kinin or bradykinin B1 and B2 recepto...

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Bibliografske podrobnosti
izdano v:Intensive Care Med Exp
Main Authors: Ding, Chao, Yang, Jack, van’t Veer, Cornelis, van der Poll, Tom
Format: Artigo
Jezik:Inglês
Izdano: Springer International Publishing 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6419653/
https://ncbi.nlm.nih.gov/pubmed/30874974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40635-019-0228-3
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