Circulating tumor cell investigation in breast cancer patient-derived xenograft models by automated immunofluorescence staining, image acquisition, and single cell retrieval and analysis

BACKGROUND: Breast cancer patient-derived xenograft (BC-PDX) models represent a continuous and reproducible source of circulating tumor cells (CTCs) for studying their role in tumor biology and metastasis. We have previously shown the utility of BC-PDX models in the study of CTCs by immunohistochemi...

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Bibliografske podrobnosti
izdano v:BMC Cancer
Main Authors: Ramirez, Arturo B., Bhat, Raksha, Sahay, Debashish, De Angelis, Carmine, Thangavel, Hariprasad, Hedayatpour, Sina, Dobrolecki, Lacey E., Nardone, Agostina, Giuliano, Mario, Nagi, Chandandeep, Rimawi, Mothaffar, Osborne, C. Kent, Lewis, Michael T., Stilwell, Jackie L., Kaldjian, Eric P., Schiff, Rachel, Trivedi, Meghana V.
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2019
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6419430/
https://ncbi.nlm.nih.gov/pubmed/30871481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-019-5382-1
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