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Alternative lengthening of telomeres (ALT) influences survival in soft tissue sarcomas: a systematic review with meta-analysis

BACKGROUND: Alternative lengthening of telomeres (ALT) is a telomerase-independent mechanism used by a broad range of neoplasms to maintain telomere length, permitting uncontrolled replication during their progression. ALT has been described in different types of sarcoma, but a comprehensive analysi...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Lawlor, Rita T., Veronese, Nicola, Pea, Antonio, Nottegar, Alessia, Smith, Lee, Pilati, Camilla, Demurtas, Jacopo, Fassan, Matteo, Cheng, Liang, Luchini, Claudio
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6419345/
https://ncbi.nlm.nih.gov/pubmed/30871494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-019-5424-8
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