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Ionotropic and metabotropic kainate receptor signalling regulates Cl(−) homeostasis and GABAergic inhibition

KEY POINTS: Potassium‐chloride co‐transporter 2 (KCC2) plays a critical role in regulating chloride homeostasis, which is essential for hyperpolarizing inhibition in the mature nervous system. KCC2 interacts with many proteins involved in excitatory neurotransmission, including the GluK2 subunit of...

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Bibliographic Details
Published in:J Physiol
Main Authors: Garand, Danielle, Mahadevan, Vivek, Woodin, Melanie A.
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2019
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6418771/
https://ncbi.nlm.nih.gov/pubmed/30570751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP276901
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