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Ionotropic and metabotropic kainate receptor signalling regulates Cl(−) homeostasis and GABAergic inhibition

KEY POINTS: Potassium‐chloride co‐transporter 2 (KCC2) plays a critical role in regulating chloride homeostasis, which is essential for hyperpolarizing inhibition in the mature nervous system. KCC2 interacts with many proteins involved in excitatory neurotransmission, including the GluK2 subunit of...

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Vydáno v:J Physiol
Hlavní autoři: Garand, Danielle, Mahadevan, Vivek, Woodin, Melanie A.
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6418771/
https://ncbi.nlm.nih.gov/pubmed/30570751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP276901
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