Distinct Subunits in Heteromeric Kainate Receptors Mediate Ionotropic and Metabotropic Function at Hippocampal Mossy Fiber Synapses

Heteromeric kainate receptors (KARs) containing both glutamate receptor 6 (GluR6) and KA2 subunits are involved in KAR-mediated EPSCs at mossy fiber synapses in CA3 pyramidal cells. We report that endogenous glutamate, by activating KARs, reversibly inhibits the slow Ca(2+)-activated K(+) current I(...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Ruiz, Arnaud, Sachidhanandam, Shankar, Utvik, Jo Kristian, Coussen, Françoise, Mulle, Christophe
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2005
Assuntos:
Cellular/Molecular
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6726035/
https://ncbi.nlm.nih.gov/pubmed/16354929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4041-05.2005
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