Llwytho...

Regulation of neuronal chloride homeostasis by neuromodulators

KCC2 is the central regulator of neuronal Cl(−) homeostasis, and is critical for enabling strong hyperpolarizing synaptic inhibition in the mature brain. KCC2 hypofunction results in decreased inhibition and increased network hyperexcitability that underlies numerous disease states including epileps...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Physiol
Prif Awduron: Mahadevan, Vivek, Woodin, Melanie A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: John Wiley and Sons Inc. 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4865579/
https://ncbi.nlm.nih.gov/pubmed/26876607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP271593
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