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Regulation of neuronal chloride homeostasis by neuromodulators
KCC2 is the central regulator of neuronal Cl(−) homeostasis, and is critical for enabling strong hyperpolarizing synaptic inhibition in the mature brain. KCC2 hypofunction results in decreased inhibition and increased network hyperexcitability that underlies numerous disease states including epileps...
Guardat en:
| Publicat a: | J Physiol |
|---|---|
| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
John Wiley and Sons Inc.
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4865579/ https://ncbi.nlm.nih.gov/pubmed/26876607 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP271593 |
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