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Histone demethylase UTX is a therapeutic target for diabetic kidney disease
KEY POINTS: Diabetic kidney disease (DKD) is a major complication of diabetes. We found that UTX (ubiquitously transcribed tetratricopeptide repeat on chromosome X, also known as KDM6A), a histone demethylase, was upregulated in the renal mesangial and tubular cells of diabetic mice and DKD patients...
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| 出版年: | J Physiol |
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| 主要な著者: | , , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
John Wiley and Sons Inc.
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6418754/ https://ncbi.nlm.nih.gov/pubmed/30516825 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP277367 |
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