The histone demethylase UTX enables RB-dependent cell fate control

Trimethylation of histone H3 on Lys 27 (H3K27me3) is key for cell fate regulation. The H3K27me3 demethylase UTX functions in development and tumor suppression with undefined mechanisms. Here, genome-wide chromatin occupancy analysis of UTX and associated histone modifications reveals distinct classe...

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Détails bibliographiques
Auteurs principaux: Wang, Jordon K., Tsai, Miao-Chih, Poulin, Gino, Adler, Adam S., Chen, Shuzhen, Liu, Helen, Shi, Yang, Chang, Howard Y.
Format: Artigo
Langue:Inglês
Publié: Cold Spring Harbor Laboratory Press 2010
Sujets:
Research Communication
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2816731/
https://ncbi.nlm.nih.gov/pubmed/20123895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1882610
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