The histone demethylase UTX enables RB-dependent cell fate control

Trimethylation of histone H3 on Lys 27 (H3K27me3) is key for cell fate regulation. The H3K27me3 demethylase UTX functions in development and tumor suppression with undefined mechanisms. Here, genome-wide chromatin occupancy analysis of UTX and associated histone modifications reveals distinct classe...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Wang, Jordon K., Tsai, Miao-Chih, Poulin, Gino, Adler, Adam S., Chen, Shuzhen, Liu, Helen, Shi, Yang, Chang, Howard Y.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2010
Soggetti:
Research Communication
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2816731/
https://ncbi.nlm.nih.gov/pubmed/20123895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1882610
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi