The histone demethylase UTX enables RB-dependent cell fate control

Trimethylation of histone H3 on Lys 27 (H3K27me3) is key for cell fate regulation. The H3K27me3 demethylase UTX functions in development and tumor suppression with undefined mechanisms. Here, genome-wide chromatin occupancy analysis of UTX and associated histone modifications reveals distinct classe...

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Bibliographische Detailangaben
Hauptverfasser: Wang, Jordon K., Tsai, Miao-Chih, Poulin, Gino, Adler, Adam S., Chen, Shuzhen, Liu, Helen, Shi, Yang, Chang, Howard Y.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2010
Schlagworte:
Research Communication
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2816731/
https://ncbi.nlm.nih.gov/pubmed/20123895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1882610
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