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Renal expression of JAK2 is high in polycystic kidney disease and its inhibition reduces cystogenesis
Autosomal dominant polycystic kidney disease (ADPKD) is the most common renal genetic disorder, however it still lacks a cure. The discovery of new therapies heavily depends on understanding key signalling pathways that lead to ADPKD. The JAnus Kinase and Signal Transducers and Activators of Transcr...
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| Pubblicato in: | Sci Rep |
|---|---|
| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group UK
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6418191/ https://ncbi.nlm.nih.gov/pubmed/30872773 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-41106-3 |
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