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Renal expression of JAK2 is high in polycystic kidney disease and its inhibition reduces cystogenesis

Autosomal dominant polycystic kidney disease (ADPKD) is the most common renal genetic disorder, however it still lacks a cure. The discovery of new therapies heavily depends on understanding key signalling pathways that lead to ADPKD. The JAnus Kinase and Signal Transducers and Activators of Transcr...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Patera, Foteini, Cudzich-Madry, Alex, Huang, Zhi, Fragiadaki, Maria
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6418191/
https://ncbi.nlm.nih.gov/pubmed/30872773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-41106-3
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