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CHD4 regulates the DNA damage response and RAD51 expression in glioblastoma
Glioblastoma (GBM) is a lethal brain tumour. Despite therapy with surgery, radiation, and alkylating chemotherapy, most people have recurrence within 6 months and die within 2 years. A major reason for recurrence is resistance to DNA damage. Here, we demonstrate that CHD4, an ATPase and member of th...
Shranjeno v:
| izdano v: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Nature Publishing Group UK
2019
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6418088/ https://ncbi.nlm.nih.gov/pubmed/30872624 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-40327-w |
| Oznake: |
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