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Regulation and pharmacological targeting of RAD51 in cancer
Regulation of homologous recombination (HR) is central for cancer prevention. However, too little HR can increase cancer incidence, whereas too much HR can drive cancer resistance to therapy. Importantly, therapeutics targeting HR deficiency have demonstrated a profound efficacy in the clinic improv...
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| 出版年: | NAR Cancer |
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| 主要な著者: | , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Oxford University Press
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7520849/ https://ncbi.nlm.nih.gov/pubmed/33015624 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/narcan/zcaa024 |
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