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Regulation and pharmacological targeting of RAD51 in cancer
Regulation of homologous recombination (HR) is central for cancer prevention. However, too little HR can increase cancer incidence, whereas too much HR can drive cancer resistance to therapy. Importantly, therapeutics targeting HR deficiency have demonstrated a profound efficacy in the clinic improv...
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| Publié dans: | NAR Cancer |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Oxford University Press
2020
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7520849/ https://ncbi.nlm.nih.gov/pubmed/33015624 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/narcan/zcaa024 |
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