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Regulation and pharmacological targeting of RAD51 in cancer
Regulation of homologous recombination (HR) is central for cancer prevention. However, too little HR can increase cancer incidence, whereas too much HR can drive cancer resistance to therapy. Importantly, therapeutics targeting HR deficiency have demonstrated a profound efficacy in the clinic improv...
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| Publicado no: | NAR Cancer |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7520849/ https://ncbi.nlm.nih.gov/pubmed/33015624 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/narcan/zcaa024 |
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