Booster Vaccination With GVGH Shigella sonnei 1790GAHB GMMA Vaccine Compared to Single Vaccination in Unvaccinated Healthy European Adults: Results From a Phase 1 Clinical Trial

The investigational Shigella sonnei vaccine (1790GAHB) based on GMMA (generalized modules for membrane antigens) is immunogenic, with an acceptable safety profile in adults. However, pre-vaccination anti-S. sonnei lipopolysaccharide (LPS) antibody levels seemed to impact vaccine-related immune respo...

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Dades bibliogràfiques
Publicat a:Front Immunol
Autors principals: Launay, Odile, Ndiaye, Augustin G. W., Conti, Valentino, Loulergue, Pierre, Sciré, Antonella Silvia, Landre, Anais Maugard, Ferruzzi, Pietro, Nedjaai, Naouel, Schütte, Lena Dorothee, Auerbach, Joachim, Marchetti, Elisa, Saul, Allan, Martin, Laura B., Podda, Audino
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2019
Matèries:
Immunology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6418009/
https://ncbi.nlm.nih.gov/pubmed/30906291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.00335
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