A Phase 2a Randomized Study to Evaluate the Safety and Immunogenicity of the 1790GAHB Generalized Modules for Membrane Antigen Vaccine against Shigella sonnei Administered Intramuscularly to Adults from a Shigellosis-Endemic Country

Shigellosis is a mild-to-severe diarrheal infection, caused by the genus Shigella, and is responsible for significant morbidity and mortality worldwide. We evaluated the safety and immunogenicity of an investigational Shigella sonnei vaccine (1790GAHB) based on generalized modules for membrane antig...

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Publicado en:Front Immunol
Autores principales: Obiero, Christina W., Ndiaye, Augustin G. W., Sciré, Antonella Silvia, Kaunyangi, Bonface M., Marchetti, Elisa, Gone, Ann M., Schütte, Lena Dorothee, Riccucci, Daniele, Auerbach, Joachim, Saul, Allan, Martin, Laura B., Bejon, Philip, Njuguna, Patricia, Podda, Audino
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2017
Materias:
Immunology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5763125/
https://ncbi.nlm.nih.gov/pubmed/29375556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.01884
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