Booster Vaccination With GVGH Shigella sonnei 1790GAHB GMMA Vaccine Compared to Single Vaccination in Unvaccinated Healthy European Adults: Results From a Phase 1 Clinical Trial

The investigational Shigella sonnei vaccine (1790GAHB) based on GMMA (generalized modules for membrane antigens) is immunogenic, with an acceptable safety profile in adults. However, pre-vaccination anti-S. sonnei lipopolysaccharide (LPS) antibody levels seemed to impact vaccine-related immune respo...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Launay, Odile, Ndiaye, Augustin G. W., Conti, Valentino, Loulergue, Pierre, Sciré, Antonella Silvia, Landre, Anais Maugard, Ferruzzi, Pietro, Nedjaai, Naouel, Schütte, Lena Dorothee, Auerbach, Joachim, Marchetti, Elisa, Saul, Allan, Martin, Laura B., Podda, Audino
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6418009/
https://ncbi.nlm.nih.gov/pubmed/30906291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.00335
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