Antibodies Elicited by the Shigella sonnei GMMA Vaccine in Adults Trigger Complement-Mediated Serum Bactericidal Activity: Results From a Phase 1 Dose Escalation Trial Followed by a Booster Extension

Shigella is the second most deadly diarrheal disease among children under five years of age, after rotavirus, with high morbidity and mortality in developing countries. Currently, no vaccine is widely available, and the increasing levels of multidrug resistance make Shigella a high priority for vacc...

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書目詳細資料
發表在:Front Immunol
Main Authors: Micoli, Francesca, Rossi, Omar, Conti, Valentino, Launay, Odile, Sciré, Antonella Silvia, Aruta, Maria Grazia, Nakakana, Usman Nasir, Marchetti, Elisa, Rappuoli, Rino, Saul, Allan, Martin, Laura B., Necchi, Francesca, Podda, Audino
格式: Artigo
語言:Inglês
出版: Frontiers Media S.A. 2021
主題:
Immunology
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC8129577/
https://ncbi.nlm.nih.gov/pubmed/34017343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.671325
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