Influence of tissue context on gene prioritization for predicted transcriptome-wide association studies

Transcriptome-wide association studies (TWAS) have recently gained great attention due to their ability to prioritize complex trait-associated genes and promote potential therapeutics development for complex human diseases. TWAS integrates genotypic data with expression quantitative trait loci (eQTL...

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Bibliographic Details
Published in:Pac Symp Biocomput
Main Authors: Li, Binglan, Veturi, Yogasudha, Bradford, Yuki, Verma, Shefali S., Verma, Anurag, Lucas, Anastasia M., Haas, David W., Ritchie, Marylyn D.
Format: Artigo
Language:Inglês
Published: 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6417797/
https://ncbi.nlm.nih.gov/pubmed/30864331
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