Tissue specificity-aware TWAS (TSA-TWAS) framework identifies novel associations with metabolic, immunologic, and virologic traits in HIV-positive adults

As a type of relatively new methodology, the transcriptome-wide association study (TWAS) has gained interest due to capacity for gene-level association testing. However, the development of TWAS has outpaced statistical evaluation of TWAS gene prioritization performance. Current TWAS methods vary in...

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Библиографические подробности
Опубликовано в: :PLoS Genet
Главные авторы: Li, Binglan, Veturi, Yogasudha, Verma, Anurag, Bradford, Yuki, Daar, Eric S., Gulick, Roy M., Riddler, Sharon A., Robbins, Gregory K., Lennox, Jeffrey L., Haas, David W., Ritchie, Marylyn D.
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2021
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC8102009/
https://ncbi.nlm.nih.gov/pubmed/33901188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1009464
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