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A simulation study investigating power estimates in phenome-wide association studies
BACKGROUND: Phenome-wide association studies (PheWAS) are a high-throughput approach to evaluate comprehensive associations between genetic variants and a wide range of phenotypic measures. PheWAS has varying sample sizes for quantitative traits, and variable numbers of cases and controls for binary...
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| Publicado no: | BMC Bioinformatics |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5885318/ https://ncbi.nlm.nih.gov/pubmed/29618318 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-018-2135-0 |
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