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Xanthohumol increases death receptor 5 expression and enhances apoptosis with the TNF-related apoptosis-inducing ligand in neuroblastoma cell lines

High-risk neuroblastoma (NB) is lethal childhood cancer. Published data including ours have reported the anti-proliferative effect of Xanthohumol (XN), a prenylated chalcone, in various cancer types suggesting that XN could be a useful small molecule compound against cancer. The TNF-Related Apoptosi...

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Bibliographische Detailangaben
Veröffentlicht in:PLoS One
Hauptverfasser: Engelsgjerd, Samuel, Kunnimalaiyaan, Selvi, Kandil, Emad, Gamblin, T. Clark, Kunnimalaiyaan, Muthusamy
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6417737/
https://ncbi.nlm.nih.gov/pubmed/30870485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0213776
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