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Xanthohumol Inhibits Notch Signaling and Induces Apoptosis in Hepatocellular Carcinoma

Despite improvement in therapeutic strategies, median survival in advanced hepatocellular carcinoma (HCC) remains less than one year. Therefore, molecularly targeted compounds with less toxic profiles are needed. Xanthohumol (XN), a prenylated chalcone has been shown to have anti-proliferative effec...

Полное описание

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Библиографические подробности
Опубликовано в: :PLoS One
Главные авторы: Kunnimalaiyaan, Selvi, Sokolowski, Kevin M., Balamurugan, Mariappan, Gamblin, T. Clark, Kunnimalaiyaan, Muthusamy
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2015
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4444108/
https://ncbi.nlm.nih.gov/pubmed/26011160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0127464
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