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Xanthohumol Inhibits Notch Signaling and Induces Apoptosis in Hepatocellular Carcinoma

Despite improvement in therapeutic strategies, median survival in advanced hepatocellular carcinoma (HCC) remains less than one year. Therefore, molecularly targeted compounds with less toxic profiles are needed. Xanthohumol (XN), a prenylated chalcone has been shown to have anti-proliferative effec...

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Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Kunnimalaiyaan, Selvi, Sokolowski, Kevin M., Balamurugan, Mariappan, Gamblin, T. Clark, Kunnimalaiyaan, Muthusamy
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4444108/
https://ncbi.nlm.nih.gov/pubmed/26011160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0127464
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