Expanding the repertoire of glucocorticoid receptor target genes by engineering genomic response elements

The glucocorticoid receptor (GR), a hormone-activated transcription factor, binds to a myriad of genomic binding sites yet seems to regulate a much smaller number of genes. Genome-wide analysis of GR binding and gene regulation has shown that the likelihood of GR-dependent regulation increases with...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:Life Sci Alliance
Autores principales: Thormann, Verena, Glaser, Laura V, Rothkegel, Maika C, Borschiwer, Marina, Bothe, Melissa, Fuchs, Alisa, Meijsing, Sebastiaan H
Formato: Artigo
Lenguaje:Inglês
Publicado: Life Science Alliance LLC 2019
Materias:
Research Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6417287/
https://ncbi.nlm.nih.gov/pubmed/30867223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.26508/lsa.201800283
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares