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Expanding the repertoire of glucocorticoid receptor target genes by engineering genomic response elements
The glucocorticoid receptor (GR), a hormone-activated transcription factor, binds to a myriad of genomic binding sites yet seems to regulate a much smaller number of genes. Genome-wide analysis of GR binding and gene regulation has shown that the likelihood of GR-dependent regulation increases with...
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| Pubblicato in: | Life Sci Alliance |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Life Science Alliance LLC
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6417287/ https://ncbi.nlm.nih.gov/pubmed/30867223 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.26508/lsa.201800283 |
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